Developmental Mechanism - Epithelial Invagination
Contents |
Introduction
Epithelia during development often undergo folding or invagination. In some cases the epithelial cells are eventually "pinched off" fron the existing epithelia to form a distinct structure, such as a tube or vesicle. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.
- Mechanism Links: Epithelial Invagination | Epithelial Mesenchymal Transition | Epithelial Mesenchymal Interaction | Morphodynamics | Tube Formation | Apoptosis | Molecular
Some Recent Findings
References
Textbooks
Reviews
Articles
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External Links
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- Mechanism Links: Epithelial Invagination | Epithelial Mesenchymal Transition | Epithelial Mesenchymal Interaction | Morphodynamics | Tube Formation | Apoptosis | Molecular
Glossary Links
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- Dr Mark Hill 2013, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
