Template talk:Lung stage table
From Embryology
2019 Update
Lung Stage | Human | Features | Vascular | |
---|---|---|---|---|
Embryonic | week 4 to 5 | lung buds originate as an outgrowth from the ventral wall of the foregut where lobar division occurs | extra pulmonary artery then lobular artery | |
Pseudoglandular | week 5 to 17 | conducting epithelial tubes surrounded by thick mesenchyme are formed, extensive airway branching | Pre-acinar arteries | |
Canalicular | week 16 to 25 | bronchioles are produced, increasing number of capillaries in close contact with cuboidal epithelium and the beginning of alveolar epithelium development | Intra-acinar arteries | |
Saccular | week 24 to 40 | alveolar ducts and air sacs are developed | alveolar duct arteries | |
Alveolar | late fetal to 8 years | secondary septation occurs, marked increase of the number and size of capillaries and alveoli | alveolar capillaries | |
Links: Species Stage Comparison | respiratory |
2018 Version
Stage | Human | Features | ||
---|---|---|---|---|
Embryonic | week 4 to 5 | lung buds originate as an outgrowth from the ventral wall of the foregut where lobar division occurs | ||
Pseudoglandular | week 5 to 17 | conducting epithelial tubes surrounded by thick mesenchyme are formed, extensive airway branching | ||
Canalicular | week 16 to 25 | bronchioles are produced, increasing number of capillaries in close contact with cuboidal epithelium and the beginning of alveolar epithelium development | ||
Saccular | week 24 to 40 | alveolar ducts and air sacs are developed | ||
Alveolar | late fetal to 8 years | secondary septation occurs, marked increase of the number and size of capillaries and alveoli | ||
Links: Species Stage Comparison | respiratory |
Lung Development Species Comparison[1] | |||||
---|---|---|---|---|---|
Species | Term | Embryonic (days) |
Pseudoglandular (days) |
Canalicular (days) |
Saccular (days) |
Human | 280 | < 42 | 52 - 112 | 112 - 168 | 168 |
Primate | 168 | < 42 | 57 - 80 | 80 - 140 | 140 |
Sheep | 150 | < 40 | 40 - 80 | 80 - 120 | 120 |
Rabbit | 32 | < 18 | 21 - 24 | 24 - 27 | 27 |
Rat | 22 | < 13 | 16 - 19 | 19 - 20 | 21 |
Mouse | 20 | < 9 | 16 | 18 | 19 |
Lung Stages Species Comparison PMID 15774522
Stage | Human | Sheep | Features | |
---|---|---|---|---|
Embryonic | week 4 to 5 | day 0 to 40 | lung buds originate as an outgrowth from the ventral wall of the foregut where lobar division occurs | |
Pseudoglandular | week 5 to 17 | day 40 to 80 | conducting epithelial tubes surrounded by thick mesenchyme are formed, extensive airway branching | |
Canalicular | week 16 to 25 | day 80 to 120 | bronchioles are produced, increasing number of capillaries in close contact with cuboidal epithelium and the beginning of alveolar epithelium development | |
Saccular | week 24 to 40 | day 120 to 148 | alveolar ducts and air sacs are developed | |
Alveolar | late fetal to 8 years | secondary septation occurs, marked increase of the number and size of capillaries and alveoli | ||
- ↑ <pubmed>10852845</pubmed>| PMC1637815 | Environ Health Perspect.