File:Mouse oocyte microtubule-associated protein 01.jpg
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Mouse Oocyte Microtubule-Associated Protein (ASPM) Expression and Subcellular Localization
Microtubule-Associated Protein (ASPM) appears to have a role in meiotic spindle assembly and meiotic progression in mouse oocytes; localized to the entire oocyte spindle at metaphase I (MI) and metaphase II (MII), colocalizing with the spindle microtubule protein acetylated tubulin (Ac-tubulin).
Legend
- GV - germinal vesicle, large centrally located oocyte nucleus.
- GVBD - germinal vesicle undergoing breakdown.
- pro-MI - Prometaphase I, spindle apparatus formed, and chromosomes attached to spindle fibres by kinetochores.
- MI - metaphase I
- MII - metaphase II
- Ac-tubulin - (green) microtubules
- ASPM - (red) Microtubule-Associated Protein
- DAPI - (blue) chromosomes.
Bar = 10 µm.
- Links: Meiosis | Oocyte Development | Mouse Development
Reference
Xu X-L, Ma W, Zhu Y-B, Wang C, Wang B-Y, et al. (2012) The Microtubule-Associated Protein ASPM Regulates Spindle Assembly and Meiotic Progression in Mouse Oocytes. PLoS ONE 7(11): e49303. PLoS ONE
doi:10.1371/journal.pone.0049303
Copyright: © 2012 Xu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal.pone.0049303.g001.jpg
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 10:07, 16 November 2012 | | 869 × 1,000 (81 KB) | Z8600021 (talk | contribs) | ==Mouse Oocyte Microtubule-Associated Protein (ASPM) Expression and Subcellular Localization== * ASPM - Microtubule-Associated Protein ===Reference=== Citation: Xu X-L, Ma W, Zhu Y-B, Wang C, Wang B-Y, et al. (2012) The Microtubule-Associated Prote |
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