File:Early mouse development cartoon.jpg

From Embryology

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Schematic view of morphological and lineage specification steps during the early mouse embryonic development

  • Starting from fertilization (E0), after three rounds of cleavages (E1–E2.5), the blastomers undergo compaction and polarization (E3).
  • Then the trophectoderm outer layer starts to separate from the inner cell mass (ICM) followed by the expansion of the blastocoel and the localization of the ICM to one part of the embryo (E3.5).
  • After this stage the endoderm is formed as a layer separating epiblast from blastocoel (E4.5).
  • After 4.5 embryonic days, the preimplantation embryo contains more than 100 cells.


Reference

<pubmed>21573197</pubmed>| PMC3088645 | PLoS Comput Biol.


© 2011 Krupinski et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 1. Journal.pcbi.1001128.g001.png

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current09:36, 9 November 2011Thumbnail for version as of 09:36, 9 November 20111,000 × 430 (81 KB)S8600021 (talk | contribs)===Schematic view of morphological and lineage specification steps during the early mouse embryonic development=== * Starting from fertilization (E0), after three rounds of cleavages (E1–E2.5), the blastomers undergo compaction and polarization (E3).

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