Developmental Signals - LIM-homeodomain
Embryology - 23 May 2024 Expand to Translate |
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Introduction
The human and mouse genomes each contain at least 12 genes encoding LIM homeodomain (LIM-HD) transcription factors.[1]
This transcription factor family contain two amino terminal LIM domains and a characteristic DNA binding homeodomain.
Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
Some Recent Findings
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More recent papers |
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: homeodomain LIM homeodomain <pubmed limit=5>LIM homeodomain</pubmed>
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Older papers |
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These papers originally appeared in the Some Recent Findings table, but as that list grew in length have now been shuffled down to this collapsible table.
See also the Discussion Page for other references listed by year and References on this current page. |
Classification
Lhx2
LH2 is expressed in the rodent in both developing and adult central nervous system.
OMIM - Lhx2
Human LIM
Functions
Developmental patterning signal.
Neural
LH2 is expressed in the rodent in both developing and adult central nervous system.
- Links: neural
Signaling Pathway
Additional Images
References
Reviews
Mallo M, Wellik DM & Deschamps J. (2010). Hox genes and regional patterning of the vertebrate body plan. Dev. Biol. , 344, 7-15. PMID: 20435029 DOI.
Articles
Search Pubmed
Search Bookshelf lom
Search Pubmed Now: LIM Homeobox
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- Nobel Prize - Medicine 1995
- OMIM - SONIC HEDGEHOG
- Genetics Home Reference
Glossary Links
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Cite this page: Hill, M.A. (2024, May 23) Embryology Developmental Signals - LIM-homeodomain. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_LIM-homeodomain
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G