File:Limb bud growth model 01.jpg

From Embryology

Limb_bud_growth_model_01.jpg(600 × 261 pixels, file size: 30 KB, MIME type: image/jpeg)

Gradient based morphogenesis.

(A) Schematic of the 3D organization of the vertebrate limb bud. Elongation occurs along the proximo-distal axis (away from the body), and the apical ectodermal ridge (AER) runs along the distal-most part of the bud.

(B) The proliferation gradient model (or growth-based morphogenesis, Morishita and Iwasa [23]) proposes that a zone of high proliferation close to the AER drives distally directed limb elongation.

Original File: Figure 1. Journal.pbio.1000420.g001.png


<pubmed>20644711</pubmed>| PMC2903592 | PLoS


Copyright: © 2010 Boehm et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current11:35, 23 July 2010Thumbnail for version as of 11:35, 23 July 2010600 × 261 (30 KB)S8600021 (talk | contribs)Gradient based morphogenesis. (A) Schematic of the 3D organization of the vertebrate limb bud. Elongation occurs along the proximo-distal axis (away from the body), and the apical ectodermal ridge (AER) runs along the distal-most part of the bud. (B) T

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