File:Heart Hypertrophy gross.jpg

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Heart Hypertrophy

Image shows a gross and microscopic section of mice heart with hypertrophy (right) and without (left). Left atrial thrombus visible on the right specimen.

Masson trichrome–stained sections of wild-type and Hdac3cko mice at 12 weeks. Deletion of Hdac3 results in cardiac hypertrophy, left atrial thrombus, and cardiac fibrosis, seen in blue (boxed section).

(Stain - Masson's Trichrome)

Reference

Montgomery RL, Potthoff MJ, Haberland M, Qi X, Matsuzaki S, Humphries KM, Richardson JA, Bassel-Duby R & Olson EN. (2008). Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice. J. Clin. Invest. , 118, 3588-97. PMID: 18830415 DOI.


Permission: Reproduction of image provided by Eric N. Olson via email.

Assessment

+ Relevant research image. + Sought the author permission for reuse. - Would have been good to include definition of hypertrophy.



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Cite this page: Hill, M.A. (2024, May 2) Embryology Heart Hypertrophy gross.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Heart_Hypertrophy_gross.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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Date/TimeThumbnailDimensionsUserComment
current14:18, 9 October 2011Thumbnail for version as of 14:18, 9 October 2011639 × 800 (59 KB)Z3329495 (talk | contribs)Image shows a gross and microscopic section of mice heart with hypertrophy (left) and without (right). Left atrial thrombus visible on the left specimen. Masson trichrome–stained sections of wild-type and Hdac3cko mice at 12 weeks. Deletion of Hdac3 re

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