File:Tooth development stage.jpg

Stages in Tooth Development

(A) Pre-patterned oral ectoderm is in close contact with cranial, neural crest ectomesenchyme. At this stage (ED 10) the odontogenic potential resides in the epithelium.

(B) The epithelial cells secrete specific signals in different areas, proliferate and form a band of epithelial tissue, the dental lamina and the dental placodes.

(C) At the sites of the dental placodes the epithelial cells proliferate and intrude within the mesenchyme forming the tooth buds. At this developmental stage the odontogenic potential is lost form the epithelium and granted to the ectomesenchyme.

(D) The bud folds in and acquires initially the form of an inverted cap and later the form of a bell.

(E) cl = cervical loop, iee = inner enamel epithelium, oee = outer enamel epithelium, pek = primary enamel knot, sek = secondary enamel knots.

"The ancestor of recent vertebrate teeth was a tooth-like structure on the outer body surface of jawless fishes. Over the course of 500,000,000 years of evolution, many of those structures migrated into the mouth cavity. In addition, the total number of teeth per dentition generally decreased and teeth morphological complexity increased. Teeth form mainly on the jaws within the mouth cavity through mutual, delicate interactions between dental epithelium and oral ectomesenchyme. These interactions involve spatially restricted expression of several, teeth-related genes and the secretion of various transcription and signaling factors."

Tooth stages: lamina | placode stage | bud stage | cap stage | bell stage | all stages | Tooth Development

Reference

Koussoulakou DS, Margaritis LH & Koussoulakos SL. (2009). A curriculum vitae of teeth: evolution, generation, regeneration. Int. J. Biol. Sci. , 5, 226-43. PMID: 19266065

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Cite this page: Hill, M.A. (2024, April 24) Embryology Tooth development stage.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Tooth_development_stage.jpg

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