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Mouse forelimb bud Tbx3 and Tbx2 expression
Establishment of posterior forelimb bud identity requires Hand2. Hand2 participates in transcriptional activation and/or upregulation of Tbx2/3 and Shh expression in the posterior mesenchyme and is required for anterior restriction of Gli3 and Alx4 expression.
- E9.75 - 27 somites
- E10.0 - 30 somites
- E10.25 - 32 somites
- E10.5: - 35 somites
Reference
<pubmed>20386744</pubmed>| PLoS Genet.
Copyright
This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
Citation: Galli A, Robay D, Osterwalder M, Bao X, Bénazet J-D, et al. (2010) Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development. PLoS Genet 6(4): e1000901. doi:10.1371/journal.pgen.1000901
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| current | 03:08, 26 April 2010 | | 955 × 436 (45 KB) | S8600021 (talk | contribs) | Mouse forelimb bud Tbx3 and Tbx2 expression. Establishment of posterior forelimb bud identity requires Hand2. * E9.75 - 27 somites * E9.75 - 27 somites * E10.0 - 30 somites * E10.25 - 32 somites * E10.5: - 35 somites Excerpt from original File name: |
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