File:Cervical intersomitic vessels.png
Mouse - Cervical Intersomitic Vessel
The vessels along the right side of the embryo and surrounding somites 1 through 16 are labelled as: DA (red), ISA (pink), ISV (blue), VTA (vertebral artery), DLAV (dorsal longitudinal anastomotical vessel) and PNVP (green) (perineual vascular plexus) , ACV (anterior cardinal vein) and CCV (cyan) (common cardinal vein) , UV (dark pink), UV plexus (purple), and PCV (blue). Somites 1, 5, 10 and 15 are numbered as S-1, S-5, S-10 and S-15.
B Branches of PECAM-1 expression originating from the tips of the ISAs (yellow arrowheads) were observed to turn towards the location of the future PCV (posterior cardinal vein).
C A second branch from the ISA was also observed to extend in a predominantly anterior direction (pink arrowheads) to connect up with other ISAs, eventually forming the DLAV. PECAM-1 expression along the location of the expected PCV was observed to lag development of the ISAs and is discontinuous (yellow arrowheads).
D The PNVP develops through remodelling of the VTA and DLAV. Branches initiate medially from the DLAV (pink arrowhead), begin to remodel into simple mesh (blue arrowhead), and eventually remodel into a fine structured capillary plexus surrounding the neural tube. Note at this stage that the first ISA has regressed.
Scale bars represent 100 microns.
ACV - anterior cardinal vein
CCV - common cardinal vein
DA - dorsal aorta
DLAV - dorsal longitudinal anastomotical vessel
ISA - intersomitic artery
ISV - intersomitic vein
OA - omphalomesenteric artery
OV - omphalomesenteric vein
PCV - posterior cardinal vein
PNVP - perineual vascular plexus
UA - umbilical artery
UV - umbilical vein
Original File: [http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0002853&imageURI=info:doi/10.1371/journal.pone.0002853.g009 Journal.pone.0002853.g009.png]
Copyright: © 2008 Walls et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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|current||11:56, 15 August 2009||600 × 462 (308 KB)||S8600021||(A) The various stages of cervical intersomitic vessel development can be segmented as visualized as surface renderings in the 16 somite mouse embryo. The vessels along the right side of the embryo and surrounding somites 1 through 16 are labelled as: D|
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